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local lymph node assay การใช้

ประโยค

  1. It has been compared with the murine local lymph node assay
  2. The test has been largely superseded by the murine local lymph node assay.
  3. Subsequently, IITRI scientists played a major role in the development and validation of the local lymph node assay ( LLNA ) for the rapid detection of agents that induce hypersensitivity.
  4. The REACH Regulation, Annex VII, paragraph 8.3 states " The Murine Local Lymph Node Assay ( LLNA ) is the first-choice method for " in vivo " testing.
  5. OTNE is classified as a skin irritant ( R38 EU DSD, H315 EU CLP ) and is positive in the Local Lymph Node Assay ( LLNA  OECD 429 ) and therefore classified as a skin sensitiser ( R43 EU DSD, H317 EU CLP ), though OTNE lacks any structural alerts for sensitisation in in-silico prediction models ( DEREK ) and is not identified as an allergen in in-vivo Human Repeated Patch Tests.

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